биоизостер, биоизостерное соединение

English-Russian Biotechnology Glossary. . 2007.

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  • Bioisostere — In medicinal chemistry, bioisosteres are substituents or groups with similar physical or chemical properties that impart similar biological properties to a chemical compound. In drug design, the purpose of exchanging one bioisostere for another… …   Wikipedia

  • bioisostere — noun Any compound, derived from another by the replacement of a group of atoms by another broadly similar group e.g. the replacement of a methyl by an ethyl group …   Wiktionary

  • Bioisosterie — ist ein Begriff aus der medizinischen Chemie. Zwei Moleküle werden als bioisoster bezeichnet, wenn sie eine biologisch vergleichbare Wirkung in vivo (also im lebenden System) zeigen und isoster sind. Ein Beispiel wären die Opiate, bei denen die… …   Deutsch Wikipedia

  • Discovery and development of integrase inhibitors — The first human immunodeficiency virus (HIV) case was reported in the 1980s. Many drugs have been discovered to treat the disease but mutations in the virus and resistance to the drugs make development difficult. Integrase is a viral enzyme that… …   Wikipedia

  • Isostere — Isosteres are molecules or ions with the same number of atoms and the same number of valence electrons. As a result, they can exhibit similar pharmacokinetic and pharmacodynamic properties.Some examples of isoteres are: *fluorine and hydrogen… …   Wikipedia

  • Fludrocortisone — drugbox IUPAC name = 9 fluoro 11,17 dihydroxy 17 (2 hydroxyacetyl) 10,13 dimethyl 1,2,6,7,8,9,10,11,12, 13,14,15,16,17 tetradecahydrocyclopenta [a] phenanthren 3 one CAS number = 127 31 1 ATC prefix = H02 ATC suffix = AA02 ATC supplemental =… …   Wikipedia

  • OpenEye Scientific Software — Type Privately held, Employee Owned, C Corporation Industry Computer software Research and development Bio …   Wikipedia

  • Agomelatine — Systematic (IUPAC) name …   Wikipedia

  • Trifluoromethyl — is a functional group in chemistry that has the formula CF3. The naming of is group is derived from the methyl group (which has the formula CH3), by replacing each hydrogen atom by a fluorine atom. The trifluomethyl group has a significant… …   Wikipedia

  • Perzinfotel — Drugbox IUPAC name = 2 (8,9 dioxo 2,6 diazabicyclo [5.2.0] non 1(7) en 2 yl)ethylphosphonic acid width= 240 CAS number= 144912 63 0 ATC prefix= ATC suffix= PubChem= 6918236 DrugBank= C=9 | H=13 | N=2 | O=5 | P=1 molecular weight = 260.184 g/mol… …   Wikipedia

  • Cresset Biomolecular Discovery — Ltd. Industry Drug Discovery, Chemistry Software Founded 2002 Founder(s) Dr. Andy Vinter Headquarters Welwyn Garden City, United Kingdom Key people Ro …   Wikipedia

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